Piracetam analogues without side effects

The effectiveness of the drug in VSD

As you know, when Vegeto is diagnosed with vascular dystonia, the brain is the first to suffer, and it requires first aid.
To disrupt normal blood flow, various diseases occur in the body: osteochondrosis, outbreaks of adrenaline and poor functioning of blood vessels. The situation is aggravated by the fact that the problem with blood flow is systematic. Thus, the brain, deprived of regular blood supply, begins to work intermittently. Without the required dose of blood, brain activity decreases, and the body faces the consequences of this starvation. The patient experiences worsening brain dysfunction if he:

  • Frequent headaches, even painful migraines;
  • Resistance to stress decreases, depression and tearfulness appear;
  • My head is spinning;
  • The stability of blood pressure indicators is disrupted;
  • Extremities are cold;
  • Extrasystole;
  • Sleep is disturbed and lethargy is present.

The use of the drug Piracetam for VSD helps to improve brain function and restore the following functions:

  • Establish metabolism in cells in the nervous system area;
  • Improvement of brain impulses. Thanks to this, memory, all body reactions and the thinking process increase;
  • Establishment of hematopoiesis;
  • Replenishing all areas of the brain with sufficient blood;
  • It becomes easier for the patient to wake up in the morning, and vigor appears.

Moreover, in addition to all the positive effects listed, Piracetam for VSD does not serve as an amplifier of mental processes. Therefore, the meaning of treating all kinds of phobias and sleep disorders is completely lost, because Piracetam does not have a sedative effect.


The doctor prescribes taking Piracetam three times a day. You need to drink 2 tablets. This is about 800 mg of the product. If improvements are visible after 2 weeks, then the amount of the drug does not increase. If significant improvements occur, the dosage can be reduced. The doctor prescribes 1 tablet of Piracetam for VSD 3 times a day. Course duration is 1.5-2 months. The dosage of Piracetam for VSD may vary depending on the patient’s weight.

Features of using the drug for VSD

The drug is often prescribed to patients with vegetative-vascular dystonia. When the brain, due to deteriorated vascular function and frequent release of adrenaline, does not receive enough blood, this negatively affects the condition of the entire body. Thus, VSD students are regularly bothered by headaches, dizziness, blood pressure surges, extrasystoles, various sleep disorders, and mood swings. Piracetam is useful for VSD, since its use promotes:

  • improving metabolism in nerve cells;
  • normalization of blood microcirculation;
  • improvement of general condition;
  • eliminating the feeling of drowsiness and weakness throughout the day;
  • activation of cognitive processes.

As a result of experiments, it was also revealed that this drug is able to enhance the effect of antidepressants, increasing their effectiveness. Therefore, Piracetam is often prescribed as an additional drug in the treatment of patients with depression.

The drug is usually prescribed to VSD patients twice a year - in spring and autumn (since symptoms worsen during these periods). As a rule, patients take 2 tablets 3 times a day. If your health begins to improve, it is not recommended to exceed the dose. If the condition improves significantly within two weeks, the dosage can be reduced to one tablet 3 times a day. Duration of treatment is up to two months. The dosage of Piracetam for VSD also depends on the patient’s weight - obese individuals need the drug in larger quantities. It is believed that it is best to start taking the drug about a month before the expected onset of exacerbation of symptoms. In any case, before you start using this nootropic, you should consult with your doctor.

The drug is contraindicated for pregnant and lactating women, children under one year old, as well as patients with heart disease, hemorrhoidal stroke and kidney problems. In addition, the drug is not recommended for patients with severe cerebral atherosclerosis, persons prone to neurotic manifestations, and patients who have undergone complex surgical operations.

The average price for the drug in Russia is 59 rubles, in Ukraine – 25 hryvnia.

Personal experience of taking it - review from Piracetam for VSD

Piracetam is my favorite nootropic. It was first prescribed to me long before the VSD crisis. Then I turned to a neurologist with complaints of frequent headaches. After an examination, I was diagnosed with vegetative-vascular dystonia.

But then, apart from headaches and fatigue, I had no other symptoms. I had no idea what panic attacks were, and how many other “special effects” dystonia could provide.

I described in more detail how my severe exacerbation of VSD began and how my PA began here.

Already during the dystonia crisis, I received prescriptions for Piracetam from various doctors whom I visited at that time. In general, over the years I have taken 7-10 courses of this medicine, I don’t remember exactly. And I always felt the result.

Piracetam does not work immediately, according to my observations – after a week, not earlier. With VSD, my condition improved significantly. Symptoms such as lethargy and apathy went away. My head hurt less, my mood improved, and my stamina increased. The concentration of attention increased very noticeably and productivity at work increased.

I’ll say right away that this drug does not help with panic attacks and anxiety right away. When I was really bad and I was treated with PA 20 times a day, I didn’t feel any effect from the nootropics at all. It wasn't worse, but it wasn't much better either.

I began to feel their effect after I got rid of panic attacks and increased anxiety.

I have never noticed a single side effect on myself. Only positive results.

It is important to understand that nootropics, unlike tranquilizers, do not have a pronounced anti-anxiety effect and act completely differently. They are used in complex therapy for psychoneurological disorders.

Nootropics do not cure anything. These are, in fact, stimulants, “vitamins”, so their effect is difficult to track.

Despite the fact that I have not had exacerbations of vegetative-vascular dystonia for a long time, I continue to take a course of Piracetam 1-2 times a year to prevent VSD (with the recommendation of a doctor).

There are many analogues of Piracetam, but I find this drug to be the most effective. In addition, it is the cheapest in price. The only exception is Lucetam. But its difference with Piracetam is only in the dosage. Lucetam has a dosage of 800 mg and 1200 mg. It is easier to take - you can take 1-2 capsules a day, instead of 3-4.

Despite the fact that I have a very good “relationship” with this nootropic, I cannot recommend it for VSD. After all, this is medicine, not candy, and such things should be prescribed by a doctor after an examination.

Here's what foreign doctors write about him:

Mechanism of action

Nootropics are a separate group of medications that can affect the higher integrative functions of the cerebral cortex. They are also called neurometabolic stimulants. The influence of these drugs improves a person’s mental activity.

The mechanism of action of nootropics is complex. They determine the normalization of the functioning of the central nervous system and ANS due to the following features:

Nootropics (Noopept, Gliatilin, Piracetam and others) additionally have a protective effect on brain tissue. The drugs increase the resistance of neurons to hypoxia and irritating factors, affect the activity of neurotransmitters, and participate in the regulation of signal transmission from the central structures of the brain to the periphery.

Nootropics easily penetrate the blood-brain barrier, which causes their direct effect on the structures of the central nervous system. At the same time, they act gently, and the maximum effect is achieved after several weeks of use.

This group of drugs is widely used in medical practice. In patients with VSD, they are stabilizers of the functioning of the ANS. They balance the sympathetic and parasympathetic divisions of the autonomic nervous system.

The classification of this group of drugs is heterogeneous. It is based primarily on their chemical composition. There are a lot of different drugs that have the same effect on the central nervous system.

Vegetative-vascular dystonia is a functional disorder caused by an imbalance of its sympathetic and parasympathetic departments.

Treatment rules

Piracetam for VSD does not require lifelong use. It is enough to undergo a course of treatment with this drug twice a year during the period of “exacerbations” (spring and autumn). Of course, in consultation with your doctor.

How much of the drug to take per day can only be decided by your doctor. Piracetam is usually prescribed for 3 doses per day. Each dose is 800 mg (2 tablets/capsules). The patient takes them before meals, drinking plenty of water. If improvements are noted within 2-3 weeks, then the drug is taken 1 tablet three times a day. The general course of treatment is 2 months. The dosage of the drug directly depends not only on the severity of VSD, but also on the patient’s weight. Asthenics, for example, require a smaller dose than obese patients.

If a teenager is being treated, it is better to start taking the drug not during the most “acute educational period”, but a month earlier in order to achieve a therapeutic effect.

Piracetam can be used with other medications for VSD: blood pressure medications, antipsychotics, cardiovascular medications. You should know that when treated with the drug, thyroid hormones begin to work more effectively, and the effect of antipsychotics is enhanced in a positive sense.

We will be grateful to you for your feedback on the use of piracetam for VSD in the comments.

Dosage

The dosage of the drug varies depending on the form of its release. Vegetative-vascular dystonia involves the use of the following types of this drug:

  • capsule containing 0.4 g of piracetam;
  • ampoule containing 0.2 piracetam;
  • tablet containing 0.2 piracetam.

This medicine is sold by prescription from a doctor, who prescribes a therapeutic dose of the drug. Dystonics may not be afraid of constantly taking Piracetam; this drug is indicated for use during periods of special exacerbations of diseases (which most often occurs in autumn and spring). After stabilization of the condition, the single dose is gradually reduced, achieving complete withdrawal of Piracetam.

According to the general rules, taking the drug looks like this:

  • Piracetam is taken 3 times a day;
  • one dose includes taking 2 capsules or tablets, it should be 800 mg;
  • The drug is taken before meals, with plenty of water;
  • after 2-3 weeks and the appearance of visible improvements, the patient switches to taking 1 capsule of Piracetam three times a day;
  • The course of Piracetam therapy is 2 months, but as prescribed by the doctor, this period can change in any direction.

The correct dosage of the drug is determined by the attending physician, taking into account the severity of the patient’s symptoms, as well as his body weight.


With the help of Piracetam, you can treat dystonia in VSD of the hypotonic type, but only with the permission of the doctor.

Andipal

If blood pressure rises against the background of VSD, then the best remedy for VSD is Andipal. The use of this medicine is especially effective in stage 1 arterial hypertension. At high blood pressure, Andipal has a mild sedative and hypotensive effect. It contains papaverine and dibazole. They have not only a symptomatic effect.

With elevated blood pressure, Andipal is taken not occasionally, but systematically. These tablets for VSD help restore the tone of the vascular walls and reduce the risk of developing hypertension.

Andipal is contraindicated for children under 14 years of age. They are recommended its analogues - Papazol and Drotaverine.

What should I take to prevent anxiety conditions that usually occur with autonomic disorder? According to reviews, the best remedy is Afobazol.

Features of using the drug for VSD

The drug is often prescribed to patients with vegetative-vascular dystonia. When the brain, due to deteriorated vascular function and frequent release of adrenaline, does not receive enough blood, this negatively affects the condition of the entire body. Thus, VSD students are regularly bothered by headaches, dizziness, blood pressure surges, extrasystoles, various sleep disorders, and mood swings. Piracetam is useful for VSD, since its use promotes:

  • improving metabolism in nerve cells;
  • normalization of blood microcirculation;
  • improvement of general condition;
  • eliminating the feeling of drowsiness and weakness throughout the day;
  • activation of cognitive processes.

The drug is usually prescribed to VSD patients twice a year - in spring and autumn (since symptoms worsen during these periods). As a rule, patients take 2 tablets 3 times a day. If your health begins to improve, it is not recommended to exceed the dose. If the condition improves significantly within two weeks, the dosage can be reduced to one tablet 3 times a day. Duration of treatment is up to two months. The dosage of Piracetam for VSD also depends on the patient’s weight - obese individuals need the drug in larger quantities. It is believed that it is best to start taking the drug about a month before the expected onset of exacerbation of symptoms. In any case, before you start using this nootropic, you should consult with your doctor.

The drug is contraindicated for pregnant and lactating women, children under one year old, as well as patients with heart disease, hemorrhoidal stroke and kidney problems. In addition, the drug is not recommended for patients with severe cerebral atherosclerosis, persons prone to neurotic manifestations, and patients who have undergone complex surgical operations.

  1. metabolic disorders (and as a result - weight gain);
  2. excessive nervousness, depression, asthenic manifestations, increased aggressiveness, sleep disorders, lethargy, trembling in the body and limbs;
  3. headache and dizziness;
  4. nausea, vomiting, diarrhea, abdominal cramps;
  5. allergic manifestations;
  6. increased sexual activity.

Tenoten

Tenoten is a homeopathic medicine with a pronounced anti-anxiety effect with an activation effect. Tenoten activates mechanisms that can limit stress. Tenoten is neither a muscle relaxant nor a sedative. Tenoten is used to treat asthenia and neuroses with an anxiety component, as well as for vegetative-vascular dystonia.

Tenoten relieves tension, instability of the psycho-emotional state, and dizziness. During intoxication, as well as during hypoxia, Tenoten acts as a neuroprotector.

Tenoten is compatible with other medications.


Tenoten relieves tension, instability of the psycho-emotional state, and dizziness. During intoxication, as well as during hypoxia, Tenoten acts as a neuroprotector.

Which is better: reviews from doctors

Many doctors rely on personal experience in using these drugs. Very positive reviews for use in pediatrics. When used by adult patients, not everything is clear, as sometimes expectations are not met.

Here are some reviews from doctors.

“Among the number of medications that promote the intellectual development of a child, Nootropil is the most promising. It has a mild effect and is very effective...” “... some of my patients did not get a positive result from nootropil. But headaches, increased agitation, and sleep disturbances are clearly evident...” “After using Piracetam, a pronounced psychostimulating effect of the drug is noted. This manifests itself both after a one-time dose and after a course of use. Patients’ moods improve, anxiety and fear disappear...”

Thus, both drugs have many positive reviews, both from patients and doctors. There are negative reviews, but they are rare. For people who intend to improve their health using the means described, only one thing can be advised. Do not self-medicate; when choosing a drug, follow the recommendations of a doctor who will help determine the size of therapeutic and preventive dosages.

Brief description of drugs

The use of nootropil or piracetam allows you to avoid and reduce the symptoms of depression, nervousness and anxiety, protects neurons (an electrically excitable brain cell that processes, stores and transmits information through electrical and chemical signals) of the brain from hypoxia (oxygen starvation, lack of oxygen in a certain organ) . An important advantage of nootropics (drugs that improve brain function) is their safety, which makes them possible to take daily and be available in pharmacies.

Indications

These funds are used:

  • to reduce the risk of stroke in patients;
  • for CNS (central nervous system) disorders;
  • when memory functions deteriorate;
  • restoration of brain activity upon recovery from a coma;
  • intoxication after alcohol, drugs and other poisons.

Contraindications

  • individual intolerance to the drug;
  • the child's age is less than 3 years;
  • pregnancy, lactation;
  • hyperkinesis (involuntary, violent movements);
  • bleeding in the brain;
  • state of excitement;
  • severe renal dysfunction.

Side effects

  • overexcitement, irritability;
  • apathy, drowsiness;
  • dizziness, headaches;
  • convulsions;
  • pressure changes;
  • abdominal pain, vomiting;
  • weight gain;
  • allergic reactions.

Brief information about the product

Prices in pharmacies:Description of “Piracetam solution for injection 20%”

Ingredients: Piracetam

An analogue of the drug Piracetam is Memotropil tablets. By using analogues of Piracetam in tablets, you can save money or improve the quality of treatment. In this case, the drug Memotropil is not a cheap drug, but it is much more effective than Piracetam in many pathologies of the body. The Piracetam analogue should be used not only in neurological practice, but also in psychiatry.

Memotropil tablets consist of an organic compound of non-proteinogenic aminobutyric acid or piracetam, a natural polymer, mealy potato carbohydrate, glycolic acid with sodium salt, stearic acid with magnesium, methyloxypropylcellulose, PEG 600, dietary supplement Sunset, silicate fatty powder, monopropyl glycol, titanium white.

Memotropil or an analogue of Pirocetam should be used for the following pathological conditions of the body:

  • age-related dementia;
  • history of Alzheimer's disease;
  • in the rehabilitation period of ischemic stroke with speech impairment, mood changes, reduction in motor and psycho-emotional activity;
  • in the treatment of alcohol dependence during the period of alcohol psychosis;
  • unsteadiness of gait in discirculatory and dysmetabolic encephalopathy;
  • with damage to the cerebellum;
  • chemical intoxication of the central nervous system;
  • brain concussion;
  • cortical myoclonus;
  • inability to concentrate and remember information in children with organic lesions of the right hemisphere of the brain.

The drug Memotropil is an analogue of Piracetam, which means that it exhibits a similar effect on the body. The drug helps the body absorb oxygen and thus reduces the need for oxygen in internal organs and systems. It has a pronounced positive effect on nerve cells and has a calming effect on muscle spasms. Has antioxidant protection. The Piracetam analogue has the property of stimulating metabolism and microcirculation in nervous tissue.

The drug does not cause drowsiness and does not have a stimulating effect on the psycho-emotional state. The drug Memotropil, a modern analogue of Piracetam, has the ability to stop blood clots at the initial stage. Reduces the amount of fibrin and plasma glycoprotein in the blood plasma.

No interactions with cardiac glycosides, xanthines, anticoagulants and ACE inhibitors were found in patients taking 600 mg of pramiracetam every 12:00.

When patients were prescribed active ingredients of the same pharmacological group as pramiracetam (for example, piracetam) simultaneously with thyroid gland extract (T 3 T 4 ), confusion, irritability and sleep disorders were observed. According to a published single-blind study in patients with severe recurrent venous thrombosis, the administration of piracetam (9.6 g per day) did not lead to a change in the dose of acenocoumarol to achieve the required INR value (International Normalized Ratio) of 2.5-3.5.

About the side effects of the product

The drug Piracetam also has side effects, among them are:

  1. Decreased level of motor activity, concentration, onset of mental retardation, increased irritability, depression, anxiety and insomnia.
  2. Changes in blood pressure, which either increases or decreases, worsening angina, exacerbation of coronary insufficiency in older people.
  3. Violation of the blood clotting process.
  4. Decreased immunity.
  5. The appearance of gastritis, diarrhea, vomiting or nausea.
  6. Loss of balance in space.
  7. The appearance of rash, itching, dermatitis on the skin, swelling of the mucous membrane.
  8. Increased libido, gaining extra pounds, the presence of chronic fatigue syndrome.

If side effects occur while taking the drug, you should consult your doctor.

Contraindications, restrictions on use and overdose

Piracetam has the following contraindications:

  • increased sensitivity to the composition of the product;
  • serious kidney pathologies;
  • increased bleeding of blood vessels or hemorrhagic stroke;
  • acute mental disorders;
  • depression caused by motor and speech excitement;
  • genetic pathology of the nervous system or Huntington's disease;
  • the period of waiting for the baby and breastfeeding.

The drug should be taken with caution when:

  • violations of the vital process or hemostasis;
  • repeated surgical interventions;
  • heavy bleeding;
  • increased thyroid function or hyperthyroidism;
  • with complex mental pathology - epilepsy.

The drug Piracetam also has other side effects, but they can only be recognized when taking the drug, depending on the individual condition of the body.

In case of overdose, increased side effects are possible.

If it occurs, it is necessary to perform gastric lavage, use of activated charcoal, and in special situations, blood lavage.

This can be plasmapheresis, hemodialysis or general infusion detoxification.

This is interesting! For what indications is Piracezin prescribed: instructions for use

special instructions

Treatment for cortical myoclonus should not be stopped abruptly, as there is a risk that attacks will recur.

During long-term treatment of elderly people, it is recommended to regularly monitor the functional state of the kidneys: depending on the creatinine clearance, the patient may need to change the dosage regimen.

During treatment with Piracetam, you should refrain from performing potentially hazardous work and be careful when driving vehicles.

During treatment, it is necessary to monitor kidney function. If adverse reactions occur, drug therapy should be stopped. This is especially true for patients with complicated renal failure. In addition, during treatment with Pramistar, it is necessary to temporarily stop driving, not engage in intellectual activities and types of work that require increased concentration.

Analogues of Piracetam

In addition to the main analogue of the domestic drug - Nootropil, Pirocetam has substitutes of weaker or stronger action, mainly different from it in chemical composition.

Fenotropil

It operates on the basis of the active substance of the same name - phenotropil, is available in the form of tablets, is a neuromodulator and nootropic, is used for astheno-neurotic syndrome, has an anti-amnestic effect, affects the inhibition of the nervous system, improves the transmission of information between the hemispheres of the brain and blood supply. Effective in extreme conditions with a single dose. In case of overdose, it can cause a panic attack and tremors of the limbs.

Glycine

The active substance is glycine, the release form is tablets. Its effects are milder than Piracetam, it is also a nootropic and psychostimulant, regulates metabolic processes in the body and brain, improves sleep and performance, and relieves psycho-emotional stress. It is also able to reduce the side effects of neuroleptics and antidepressants, is non-toxic, can be used in children 1/2-1 tablet sublingually, up to 3 times a day.

In addition, the following analogues of Piracetam are distinguished:

  • Noocetam
  • Stamin
  • Exotropil
  • Pyramem
  • Pyratropil

Analysis of pros and cons

When choosing Piracetam as an effective means for increasing brain performance and mental activity, one must not forget that this drug:

  • valued for normalizing connections between both hemispheres of the brain;
  • helps improve synaptic conductivity of neocortical structures;
  • tones cerebral blood flow;
  • restores the natural functionality of the brain;
  • promotes protective normalization in the event of hypoxia and identified intoxication;
  • significantly reduces the rate of chemical reactions if platelet aggregation occurs.

By preventing cells from sticking together in the initial stage of blood clot formation, the drug helps to improve the health of the body and maintain a high level of human performance.

The listed advantages of Piracetam do not exclude its disadvantages, among which it is particularly worth highlighting:

  • has certain contraindications for use, which can be individually determined by the attending neurologist;
  • capable of provoking and causing undesirable manifestations of central nervous system failures;
  • promotes the development of hypertension;
  • causes an exciting side effect;
  • if the functions of the nervous system are impaired, not only drowsiness and nervousness may be observed, but also depression, apathy, and bad mood may appear;
  • when taking tablets systemically, severe headache, dizziness, insomnia, anxiety are often observed, and hallucinations are possible;
  • the digestive system often reacts to nootropic drugs with sudden nausea or vomiting, severe abdominal pain;
  • patients prone to allergies sometimes notice a rash, swelling, itching and even hives.
  • in certain situations, when metabolic processes are disrupted, the immune system is malfunctioning, a sharp increase in body weight may be observed, which is observed when taking nootropic tablets.

Piracetam is prescribed by a neurologist and prescribes this effective remedy for his patients to improve cerebral circulation.

For adults and children, regardless of age, this medication is prescribed:

  • after suffering traumatic brain injuries;
  • for hyperactivity and anxiety in children;
  • if there is a lack of attention, general concentration is impaired;
  • as a means of improving memory and mental performance;
  • recommended for children - to improve speech, improve learning ability at school or other educational institutions.

It is not always possible to find this popular drug in pharmacies and, knowing its analogues, as well as the compatibility of Piracetam with other medications, you can more effectively influence the activity of the brain and the entire nervous system, and many people are pushed to look for substitutes by the desire to try something new, better and more efficient.

Composition of Piracetam, release form

The product has various types in different concentrations of the active component, which simplifies its use. The most common are tablets and capsules. The former come in two dosages - 200 and 400 mg, the latter are released in a concentration of 400 mg. The solution in ampoules is used intravenously and intramuscularly. Piracetam ampoules contain 200 mg of working substance per ml. Considering that the containers are 5 ml in volume, they contain 1000 mg of the active substance.

The main ingredient in Piracetam is the component of the same name. This is a nootropic that has a positive effect on metabolic processes, thanks to which the concentration of ATP in the tissue increases and the reproduction of ribonucleic acids and phospholipids improves.

The drug increases blood flow to the cerebral cortex, mental processes receive positive dynamics. The drug does not dilate blood vessels and does not slow down the union of activated platelets. Piracetam creates a protective barrier in case of brain damage due to hypoxia, intoxication, electric shock, increases beta and alpha activity, and reduces unintentional eye movements (vestibular nystagmus). The drug is able to stimulate glycolytic processes, which accelerates the processing of glucose.

The connection between the right and left hemispheres is being established, synoptic conduction in neocortical structures also has positive dynamics. Cerebral function is being restored and stabilized. With all this, Piracetam does not cause such side effects as drowsiness. This is important for people whose activities require quick reactions. Has no psychostimulating effect.

Kemodin

Kemodin represents a pharmacotherapeutic group of nootropic and psychostimulant drugs. Produced by the Italian pharmaceutical laboratory Lizapharma S.P.A. Esseti Pharmaceutical S.R.L.

Release form and composition. Available in the form of a solution for intravenous and intramuscular injections. One milliliter of the drug contains 250 mg of citicoline sodium. One ampoule contains 500 mg of the active ingredient and 2 ml of medication. 4 ml ampoules containing 1 g of citicoline sodium are also available. Auxiliary component: water for injection.

Treatment with Kemodin is indicated for acute forms of insufficient cerebral circulation, as well as during the treatment or rehabilitation of cerebral circulatory disorders. Prescribed during the elimination of the consequences of traumatic brain injury.

Contraindications

Prohibited in cases of known hypersensitivity or high excitability of the autonomic nervous system.

One in ten thousand patients experiences hallucinations, increased or decreased blood pressure, tachycardia, and dyspnea. Skin rashes or digestive system disorders occur with the same frequency.

What is the difference between Phezam and Nootropil?

Phezam contains substances that complement this product and make it unique. They improve cerebral circulation and have a positive effect on the blood vessels of the brain. To understand which is better, Phezam or Nootropil, it should be noted that these two drugs are identical. They both have an equally effective effect on the central nervous system and improve memory, as well as human mental activity.

It must also be remembered that Phezam is prescribed in cases where Nootropil causes a huge number of side effects in patients, thereby not bringing any benefit. But if “Nootropil” is not suitable for some reason, then “Phesam” with the same probability may not be suitable.

Pharmacodynamics and pharmacokinetics

The active ingredient of the drug Pramistar belongs to nootropic drugs, racemates, pyrrolidine derivatives. The product improves memory and learning ability, activates motivation processes.

The mechanism of action of this substance is not yet fully understood, but it is known that it activates neuronal activity and high-affinity uptake of choline in cholinergic areas of the brain. The drug takes part in the synthesis of phosphatidylcholine, improves the plasticity of neurocyte membranes, and restores their structure.

The medicine does not have a sedative or other effect on the autonomic and central nervous system.

Pramiracetam increases the time during which patients can concentrate on something, activates mental activity in general, and improves memory. Microcirculation of brain tissue is normalized, the structure of the reticular formation is restored. The medicine is also quite effective as an antidepressant.

After taking the tablet, the active substance is quickly and almost completely absorbed into the systemic circulation. The maximum level of pramiracetam in the blood is achieved after 2 hours. The half-life is 6 hours. The drug is not metabolized in the liver and does not bind to plasma proteins. It is excreted unchanged in the urine.

Compound

400 mg tablets contain the following substances:

  • piracetam;
  • silicon anhydride;
  • magnesium stearate;
  • lactose;
  • titanium dioxide;
  • gelatin.

The complex of substances presented allows:

  • improve cognitive processes;
  • increase mental performance;
  • increase concentration;
  • improve metabolic processes;
  • normalize blood microcirculation;
  • improve cerebral blood flow;
  • normalize the connection between the cerebral hemispheres;
  • inhibit platelet aggregation;
  • restore membrane elasticity of red blood cells.

In addition, it helps to prolong the time of hematopoiesis.

Combined effect of vinpocetine and piracetam

A drug that improves cerebral circulation (Vinpocetine) delivers glucose and oxygen to brain tissue, reduces blood viscosity, and increases blood flow.

The medication helps speed up the treatment process in patients suffering from impaired memory and mental function.

The drug Vinpotropil, as a combination drug, is intended for the symptomatic treatment of chronic cerebral circulatory failure. The effectiveness of the medicine appears after long-term use.

There is only one question, but the most difficult one: which is better?

Detailed comparative characteristics of Piracetam analogs: which is better for different situations.

When analyzing the characteristics of Piracetam synonyms, identifying obvious pros and cons for specific situations or for different approaches, it is worth highlighting the following drugs:

  1. Nootropil . Piracetam is classified as a generic medicine and is a domestic analogue of the original drug Nootropil. Therefore, there is not much difference in the choice of these drugs, which have a direct effect on the brain, increasing its performance and stimulating mental activity. If we consider the price, then for many domestic drugs it is significantly lower. Cheaper generics attract the attention of those who are used to saving on this type of stimulant. Experts classify Piracetam as a less purified synonym that can have side effects not only on the kidneys, but also on the liver. But all this is individual. Both drugs are used to escape the negativity of chronic alcoholism or are prescribed after a stroke (rehabilitation period).
  2. Lucetam . The drug is prescribed to restore memory faster and more effectively, to improve the activity of the entire central nervous system; it is recommended to initially consult with your doctor, or go to the clinic for advice from a neurologist. If you need to increase brain performance, avoiding psychostimulating and sedative effects, it is better to choose Lucetam, because to obtain the same effect from Piracetam, it is prescribed 12 tablets per day. Lucetam is preferable because the high concentration of piracetam in it allows you to prescribe the drug with fewer tablets, and the duration of the recovery course will be from 3 weeks.
  3. Cinnarizine . Possible combination with Piracetam. Everything will depend on the situation, the specific state of affairs. For chronic cerebrovascular insufficiency, hypertension, cognitive deficit, acute cerebral ischemia, dizziness, staggering when walking, a complex of these drugs is recommended. The combined complex of these medications is characterized by a pronounced antihypoxic effect, accompanied by vasodilating and nootropic reactions of the body. Blood flow in the ischemic area will improve, metabolic processes will be normalized. When taken, the reaction to vasoconstrictor biogenic drugs will significantly decrease. If you have to use Dopamine, Norepinephrine, Epinephrine, or Serotonin, Vasopressin, Angiotensin are prescribed, you need to take care to normalize the tone throughout the body.
  4. Cavinton . To improve brain metabolism, it is better to choose Cavinton. Unlike Piracetam, it is able to selectively improve blood circulation in the cerebral hemispheres, increasing the cerebral fraction in the minute volume of blood, reducing the resistance of the vessels of the circulatory system of the brain, without directly affecting the circulatory system in the body.
  5. Vinpocetine . In modern pharmacy, a combined complex of these medications (together with Piracetam) is recommended for diseases of the central nervous system, when the intellectual activity of the brain is reduced, insufficient blood circulation to the head is observed, and patients undergo rehabilitation after strokes. The Vinpocetine+Piracetam complex is recommended after head injuries in Meniere's syndrome, for the effective prevention of akinetosis, and in cases of migraine.
  6. Mexidol . Among the popular substitutes for Piracetam, Mexidol is recommended. In neurology it is used as an antioxidant component. The doctor prescribes it for dementia, neuroses, psychoses, withdrawal symptoms (in psychiatry, for the treatment of alcoholism), acute circulatory disorders in the brain, vascular atherosclerosis (dyscirculatory encephalopathy), vegetative-vascular dystonia. Medications are recommended for identified speech disorders, memory loss and decline, disruptions in intellectual activity, identified attention disorders, and impaired concentration. If the liver or kidney functions are impaired, or the body is hypersensitive to the drug, Mexidol is not recommended for use and has contraindications.
  7. Phenotropil . A drug of better quality than Piracetam, with the desired clinical effect, is most often prescribed for head injuries and during the rehabilitation period, as well as if it is necessary to significantly improve the metabolic processes of the brain. Phenotropil can be found in pharmacies as Phenylpiracetam, Carphedon, Phenylpiracetam - these medications are distinguished not only by their mnemotropic or nootropic effect, but also by their psychostimulating and antidepressant effects on the central nervous system. They differ in anticonvulsant and anxiolytic manifestations. They are prescribed by the attending physician after examination and passing the necessary tests.
  8. Pantogam . Being a nootropic medicine, it at the same time has a different effect on the human body than Piracetam. Like Phenibut, it can effectively reduce brain tension, reducing anxiety, and promoting healthy sleep. Pantogam is characterized by an anticonvulsant effect, reducing excitability, while streamlining behavior, normalizing the psyche and motor skills of movements. It is valued as an effective remedy that helps quickly increase physical and mental performance. At the same time, Piracetam tends to quickly improve metabolic processes in the brain.

Each case is individual and taking Piracetam analogues instead or in conjunction with it or other means should be discussed with a neurologist or other attending physicians.

Expert neurologists will be able to more substantively analyze the condition of their patients, identify special intolerance to individual drugs or tablets, ampoules, injections, and droppers prescribed in combination.

Diseases of the nervous system, as well as decreased brain function, are treated with nootropic drugs such as Piracetam. It effectively helps restore cognitive abilities, memory and attention, improves metabolic processes. Due to side effects and some features of the medicine, Piracetam is not suitable for everyone - analogues are selected according to the individual needs of patients.

What can replace Piracetam?

When choosing similar medications, it is important to pay attention to the active substance. Piracetam is the basis of almost all generic versions of the drug in question, but many of them are much better tolerated. This is due to more thorough purification of chemical compounds and the high level of technology used in the production process.

Analogues of Piracetam without severe side effects:

  • Pirabene;
  • Lutsetam;
  • Nootobril;
  • Noocetam;
  • Memotropil;
  • Pyratropil;
  • Pyramem;
  • Escotropile;
  • Stamin;
  • Piracetam MS;
  • Biotropil;
  • Noopept;
  • Cerebril.

It is worth noting that Piracetam, in fact, itself is a generic version of another drug - Nootropil. The described medication is preferred in domestic medicine because it has a lower cost. However, there have been no long-term clinical studies of Piracetam and there is no experimental evidence regarding its effectiveness. It is important to take this information into account when choosing a treatment.

Nootropil or Piracetam – which is better?

Although both presented drugs are based on the same active substance and its concentration in them is the same, there are a number of differences between Piracetami and Nootropil. For example, the latter has fewer side effects and requires a shorter course of treatment.

According to consumer reviews, it is clear that Nootropil is more effective. The main disadvantage of the drug is its high cost due to foreign production.

Can Cinnarizine be substituted for Piracetam?

These agents have similar actions, for example, improving blood circulation in brain tissue, strengthening membrane films and increasing the intensity of metabolic processes in cells. But it should be remembered that Cinnarizine is prescribed directly for the treatment of blood flow pathologies, as well as reducing the frequency of cerebral vascular spasms. This drug does not stimulate or restore memory, attention, or concentration abilities, unlike Piracetam. Therefore, it cannot be considered as an analogue or generic.

Such a drug as Piracetam has been known for quite a long time. Years pass, but the product does not lose its position. It is still prescribed by doctors for a variety of neurological pathologies. What is the secret of this medicine? Are there any analogues? Piracetam is a fairly popular medicine, so our review will be useful to many.

Comparison of side effects of Lucetam and Nootropil

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Lucetam's side effects are almost the same as Nootropil's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Lucetam are similar to Nootropil: how quickly the body recovers after taking it and whether it recovers at all.

How to take Vinpocetine and Piracetam together

Tablets of the combined product are taken 1 pc. 2-3 times a day 4 hours before bedtime. The medication can be taken before or after meals. The course of therapy is 1 month.

Before starting intravenous administration of drugs, prepare a solution. Mix 2 ampoules of the drug Vinpotropil with 0.5 liters of 0.9% sodium chloride solution. The finished composition is administered intravenously. The drip is placed on the patient 3 hours before bedtime.

The solution is injected into a vein at a rate of 80 drops per minute. The course of therapy lasts 14 days, then the patient takes a break for 60 days. If the patient's condition improves, he continues treatment with tablets.

Comparison of addiction between Lucetam and Nootropil

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Lucetam is quite similar to the similar values ​​in Nootropil. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body.

And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Lucetam has quite a small value of “syndrome”, however, the same as Nootropil.

Directions for use and doses

The recommended dose is 600 mg every 12:00. The total daily dose should not exceed 1200 mg per day. A clinically significant effect can be expected no earlier than 4-8 weeks of treatment.

Elderly patients. No dose adjustment is required.

Patients with renal failure. In renal failure, there is a delay in the excretion of pramiracetam. The clinical significance of delayed excretion of pramiracetam in renal failure has not been determined. Therefore, patients with renal failure should use the drug with caution, and if undesirable effects occur, discontinue it, since these may be signs of accumulation of the active substance in the body. The use of Pramistar in severe renal failure is contraindicated.

Possible negative reactions

Even short-term use of Nootropil can cause the following negative reactions in the patient:

  • increased irritability;
  • nervousness;
  • state of restlessness, anxiety;
  • depression;
  • hallucinations;
  • sleep disturbances, including insomnia;
  • gastrointestinal disorders;
  • nausea, vomiting;
  • skin irritation, rash;
  • epileptic seizures;
  • weight gain.

If adverse reactions occur, it is necessary to adjust the dose of Nootropil.

Why is Piracetam prescribed?

The combined drug is prescribed to patients with conditions such as:

  • memory loss in people over 60 years of age;
  • dizziness;
  • mood swings caused by vascular pathology;
  • treatment of sickle cell anemia.

Piracetam is prescribed to patients with mood swings caused by vascular pathology.

The medication is used in the complex treatment of diseases in children such as:

  • speech disorder;
  • prevention of crisis in sickle cell anemia.

What are the indications for prescribing piracetam?

Despite the numerous analogues available, Piracetam is quite in demand for a variety of pathologies. The medicine is prescribed if the patient is diagnosed with:

  1. Chronic cerebrovascular insufficiency, which manifests itself as dizziness, pain, speech and memory disorders.
  2. Ischemic stroke and its consequences.
  3. Dementia – vascular, senile. Alzheimer's disease.
  4. Psychoorganic syndrome. Even those caused by alcoholism.
  5. Traumatic brain injury and its consequences.
  6. Acute neuroinfection of a viral nature.
  7. Consequences of intoxication. Including pathologies caused by taking morphine, barbiturates, ethanol, amphetamine.
  8. Pathologies of the nervous system, characterized by a reduced level of wakefulness, behavioral disorders, deterioration of intellectual functions, and emotional disturbances.
  9. Depression resistant to antidepressant treatment.
  10. Epilepsy.

The drug Piracetam is often included in combination therapy to combat sickle cell anemia. To prevent the development of vaso-occlusive crisis, the patient is recommended to take a tablet form of the drug. Piracetam injections can stop the pathological process.

The use of the drug is advisable for many pathologies: dizziness, sluggish state. It demonstrates an excellent effect in the treatment of neurological, somato-vegetative consequences resulting from the use of antipsychotic or psychotropic drugs.

The drug is in demand in pediatrics. It is prescribed for complications of central nervous system lesions, mental retardation, cerebral palsy, intellectual disability, mental retardation, memory impairment, speech disorders, and learning disabilities.

When purchasing Piracetam, the patient immediately reads the instructions for use. After all, you yourself, regardless of the doctor’s prescription, carefully read the readings again. The drug can be prescribed by different specialists, but it is most widely used in psychiatry, neurology, narcology and pediatrics.

Indications in psychiatry:

  • Depression and neurotic conditions;
  • Slowness of thought and speech processes;
  • Apathy to what is happening, lethargic state;
  • Decrease in intelligence;
  • Memory loss;
  • Alzheimer's, Pick's, Parkinson's.
  • High blood pressure, atherosclerosis;
  • Diseases of the vascular system;
  • Headache;
  • Poor sleep and memory impairment;
  • Violation of activity;
  • Consequences of various intoxications and injuries.

Piracetam - indications for use in pediatrics:

  • Congenital mental defect syndrome;
  • Brain disorders;
  • Underdevelopment;
  • Cerebral palsy in children.

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  • Acute alcohol poisoning;
  • Overdose of barbiturates, morphine, phenamine;
  • Asthenia and mental disorders in alcoholism;
  • Relief of critical conditions in drug addiction.

Overdose symptoms

When taking higher doses of the drug, symptoms such as severe pain, abdominal pain and bloody diarrhea are observed.

If an overdose is suspected, it is necessary to induce vomiting in the patient by any available means, as well as perform gastric lavage. At the discretion of the doctor, symptomatic therapy is prescribed.

No other symptoms of an overdose of Nootropil were identified. There have been no cases of death when taking high doses of the drug in medical practice.

Storage conditions and shelf life

Piracetam belongs to the group of medicines dispensed from pharmacies strictly according to a doctor's prescription.

This drug can only be used as prescribed by a doctor.

Piracetam is a synthetic nootropic drug widely used in psychiatric and neurological practice.

https://www.youtube.com/watch?v=oOGwLkRJb9s

It is recommended to keep the medicine in its original packaging, in a cool place out of reach of children. The shelf life of the medicine is 3 years.

It is recommended to keep the medicine out of the reach of children.

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