Calming tablets Adaptol - negative reviews. Neutral. Positive. + Leave a review Negative reviews Anna Appointed by a neurologist, did NOT help and greatly worsened the situation, became more divisive

Sedatives are a group of psychotropic substances that are often prescribed to patients with various pathologies, both mental and somatic. The most effective sedatives are tranquilizers. Their use is limited by a large number of contraindications and side effects. The exception is adaptol, a drug that has a mild sedative effect.

Compound

The drug contains the main active ingredient, as well as a number of auxiliary compounds. The active ingredient of adaptol in tablets and capsules is mebicar. The amount in each tablet or capsule corresponds to the dosage of the medication indicated on the package.

Excipients of the product in capsule form are calcium and titanium compounds, cellulose and gelatin. The tablets contain excipients such as calcium stearate and methylcellulose. Only the active substance has an effect on the body. The remaining components have a very low concentration and do not affect health. They are necessary in order to form a capsule or tablet.

Composition and properties of Adaptol

One capsule contains:

• active substance - mebicar 300 mg;
• excipients: methyl cellulose, calcium stearate;
• composition of the capsule body and lid: gelatin, titanium dioxide E171.

Description: hard gelatin capsules No. 0 white/white, containing white or almost white powder, are allowed in the form of a compacted column that crumbles when touched by a glass rod. Heterogeneity in particle size is allowed.

Pharmacotherapeutic group: Psychotropic drugs. Anxiolytics. Other anxiolytics.

ATX code: N05BX

Pharmacological properties

Adaptol is considered one of the mildest tranquilizers in its action. Its mechanism is based on the influence on the limbic and hypothalamic structures of the central nervous system. The limbic region of the brain is responsible for mood, emotions, behavior and memory. An imbalance of substances in its neurons leads to mental disorders.

The hypothalamus is responsible for the connection between mental functions, the nervous system and the work of other organs and systems. When there is an imbalance of mediators in this structure, neurotic states and somatoform disorders arise.

The advantage of adaptol is that it influences not just one specific type of mediator, but establishes a balance between all the significant substances of the listed brain structures. Adaptol affects the concentration of gamma-aminobutyric acid and acetylcholine - inhibitory mediators, as well as norepinephrine and serotonin - excitation mediators. This allows you to establish a balance between excitation and inhibition of the central nervous system, which is the main stage in getting rid of many mental and neurological disorders.

In addition, adaptol is an antioxidant. It protects brain cells from the influence of a number of toxic substances, including reactive oxygen species. Another important property of the drug is the improvement of nerve cell trophism. This mechanism of action is called nootropic, it leads to an improvement in cognitive functions of the psyche.

special instructions

The instructions for use of Adaptol indicate that cases of addiction, physical or mental dependence on the drug, withdrawal syndrome (negative reaction of the body to stopping taking the drug) have not been established. In some individual cases, the medicine can cause weakness and a decrease in blood pressure, which negatively affects the speed of mental and physical reactions. During the course of treatment, driving a car and performing complex work with machinery should be done with caution.

Indications

The medicine is used in the vast majority of cases in psychiatric and psychotherapeutic practice. However, it can be used by doctors of other profiles. For example, neurologists and cardiologists. The use of adaptol is justified in the following cases:

• Neurotic disorders accompanied by increased irritability, aggression, anxiety;
• Emotional lability as a symptom of any disease;
• Neurasthenia due to general fatigue;
• Somatoform and psychosomatic disorders, including non-anginal heart pain;
• Clinically pronounced premenstrual syndrome, deterioration of well-being during menopause;
• Psychological stressful situations in order to improve the body’s adaptive capabilities;
• The need to protect nerve cells from damaging factors, as a cerebroprotector;
• Quitting smoking as a drug that reduces tobacco addiction;
• Infectious pathology accompanied by productive psychotic symptoms;
• State of hypomania or residual effects of schizophrenia;
• Hallucinosis or anxiety-delusional disorder without severe behavioral disturbances.

In addition, adaptol is prescribed in conjunction with antipsychotics. This makes it possible to reduce the manifestations of a number of side effects associated with neurological disorders. Mebicar has been proven to improve the tolerability of antipsychotic therapy.

Contraindications

Adaptol has a minimal number of contraindications. This may be due to little study of the drug. Adaptol is a relatively new product that is currently undergoing post-marketing trials. Several clear contraindications have been identified. First of all, these include individual intolerance to mebicar or other components of the product.

It is also worth considering that the medicine has not undergone clinical trials on pregnant women, its ability to penetrate the placenta and into breast milk has not been studied. Adaptol is not prescribed to pregnant women, regardless of trimester, or to women during lactation.

It is necessary to study in more detail the possibility of using adaptol in children.

Adaptol price, where to buy

The price of Adaptol 500 mg is on average 500 rubles per package of 20 pcs. The price of Adaptol in Kharkov and other cities of Ukraine is on average 150 hryvnia. You can buy the product at any pharmacy. Whether the drug is available with a prescription or not, you should ask the doctor who prescribes the drug.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Adaptol tablets 500 mg 20 pcs. Olainfarm JSC
  RUB 713 order

Pharmacy Dialogue

• Adaptol (500 mg tablet No. 20)Olainfarm OA

  RUR 722 order

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Pharmacy24

• Adaptol 300 mg No. 20 capsules AT "Olainfarm", Latvia
  177 UAH. order
• Adaptol 500 mg N20 tablets AT "Olainfarm", Latvia

  272 UAH. order

PaniPharmacy

• Adaptol capsule Adaptol (mebicar) caps. 0.3g No. 20 Latvia, Olainfarm JSC

  185 UAH order

• Adaptol tablets Adaptol (mebikar) tablets 0.5g No. 20 Latvia, Olainfarm JSC

  285 UAH. order

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Side effects

The most common side effects of adaptol include a decrease in blood pressure and a decrease in body temperature by a degree and a half. These side effects are associated with the effect of the drug on the centers of the autonomic nervous system. Arterial hypotension and hypothermia do not require specific treatment or drug withdrawal. When taking adaptol in constant dosages, these side effects go away on their own.

Drowsiness, fatigue and decreased libido occur much less frequently when using adaptol compared to other psychotropic substances. However, some patients taking the drugs note the presence of these symptoms.

Some patients may develop an allergic reaction. Most often it is limited to symptoms such as rash and itching. Less commonly, a more serious complication occurs - bronchospasm, leading to suffocation. If any hypersensitivity develops, the drug should be discontinued. It cannot be re-prescribed, since allergies are a direct contraindication.

Disturbances from the digestive system are extremely rare. They are not specific. Patients may complain of heartburn, belching, nausea, and vomiting. When the dosage is reduced, these symptoms disappear.

The advantage of adaptol over other psychotropic substances is the absence of withdrawal syndrome or dependence. Even long-term use of the drug does not threaten the development of pathological conditions after stopping its use. It is necessary to consider in more detail the possibility of using adaptol with alcohol.

Indications for use

As indicated in the instructions, Adaptol can have a calming effect on the nervous system. After using Adaptol, there is an improvement in performance and mental activity, and it is possible to concentrate better. At the same time, as reviews of the drug Adaptol indicate, it does not cause symptoms such as increased emotional activity, irritability, or psycho-emotional instability. After using Adaptol, there is no feeling of euphoria, as with drugs or when taking potent tranquilizers. Adaptol can be used both during study or work, and while driving vehicles. It does not cause impaired coordination of movements. But caution should be observed during the working day when taking Adaptol.

The use of Adaptol is appropriate for neuroses, increased irritability, anxiety, and regularly and unreasonably occurring feelings of fear. Adaptol's instructions indicate that it can be used in combination with other tranquilizers and antipsychotic drugs, softening their effects, improving tolerability and eliminating possible neurological side effects. The only exceptions are drugs with a hypnotic effect - their effect is enhanced when taken together with Adaptol, therefore, for the treatment of sleep disorders, the drug is recommended to be prescribed only in combination with other medications.

Adaptol is prescribed to those who have decided to quit smoking because it reduces the need for nicotine. Adaptol's instructions recommend prescribing it in such cases as part of complex therapy for those wishing to get rid of nicotine addiction.

Due to its mild neuroleptic effect, Adaptol is used in the treatment of cardialgia.

Overdose

The exact doses that can lead to an overdose of the drug are unknown. If you take a large number of tablets or capsules, you may develop conditions corresponding to side effects. Increasing the dose increases the risk of allergic reactions, including bronchospasm. In addition, the probability of developing pathology of the digestive system is dose-dependent. The possibility of a toxic effect on the central nervous system, manifested in pathological drowsiness, up to impairment of consciousness, cannot be ruled out.

If an overdose is suspected, it is necessary to carry out a set of detoxification measures. First of all, rinse the victim’s stomach and give a siphon enema. In severe cases, the patient is hospitalized in the intensive care unit, where infusion therapy is performed.

How to take the medicine correctly?

"Adaptol" in tablet form must be taken orally at a dose of five hundred milligrams (one tablet) two to three times a day, depending on the severity of symptoms. In this case, the duration of therapy can vary from a couple of days to several months.

As a drug that can reduce symptoms of abstinence, Adaptol should be taken orally from five hundred to one thousand milligrams (one or two capsules) three times a day, the duration of treatment is twenty-one days.

According to the instructions for use of Adaptol, it is known that the capsules can be taken regardless of nutrition. In most cases, patients are recommended to use three hundred to five hundred milligrams of the active ingredient two to three times a day.

The drug is prescribed for a period from two days to three months, depending on the diagnosis and characteristics of the course of the disease. The instructions for use of the drug indicate that the maximum single dosage of the active substance is three grams, the maximum daily dosage is ten grams. When treating nicotine addiction, the drug is prescribed in a dosage of 0.9 grams three times a day.

The medication may have a negative effect on your ability to drive, as it may cause weakness and dizziness (due to low blood pressure). It is recommended to discontinue the use of Adaptol if allergic manifestations occur in the form of skin itching or skin rashes.

As a rule, the drug is well tolerated by patients. The drug is practically non-toxic, but with a significant increase in dosage it can cause increased side effects:

1. Hypotension (a long-term condition of the body characterized by low blood pressure).
2. Dizziness.
3. Migraine (a neurological disease, the most common and characteristic symptom of which is episodic or regular severe pain).
4. Dyspeptic disorders (functional disorders of the digestive system).

To eliminate these signs, it is recommended to rinse the stomach and carry out comprehensive and detoxification treatment.

Instructions for use

Adaptol is taken twice or thrice a day, regardless of meals. The dose of the drug is not titrated, the average therapeutic dosage is prescribed immediately. Adults take 300 or 500 mg 2-3 times a day at the same time. Teenagers - 250 mg twice a day.

Adaptol does not accumulate in the body, its effect is noticeable immediately after the start of administration. In some cases, a few days of treatment are sufficient.

Treatment is allowed for a maximum of 2-3 months. The maximum dose taken at one time should not exceed 3000 mg.

To treat nicotine addiction, the concentration is increased. It is recommended to take 500-1000 mg of the drug three times a day for 1.5 months. During the course of treatment, it is not recommended to drive vehicles or engage in activities that require increased concentration.

Pharmacological action of Adaptol

According to the instructions, Adaptol is a tranquilizer. The chemical composition of the product is quite close to the natural metabolites of the human body. The drug molecule consists of 2 methylated urea fragments, which are part of the bicyclic structure.

The drug affects the activity of structures that are part of the limbic-reticular complex, namely the emotiogenic zones of the hypothalamus. In addition, Adaptol affects all four main neurotransmitter systems: choline-, GABA-, serotonin-, adrenergic. Thus, the drug promotes their integration and balance, however, the drug does not have a peripheral adrenergic effect.

When exposed to the drug in humans, there are no disturbances in coordination of movements and consciousness. The drug does not create the effects characteristic of a narcotic state - a feeling of euphoria and high spirits.

Despite the fact that Adaptol does not have a hypnotic effect, it enhances the effect of hypnotics. Taking this drug in combination with the latter, a person notices a significant improvement in the quality and duration of sleep in cases of sleep disturbance.

According to the instructions for Adaptol, the nootropic effect of the drug is manifested in the following: in the course of numerous clinical studies, it was revealed that the drug increases a person’s mental abilities. Taking drugs increases the speed and coherence of thinking, the logic of thoughts and statements, improves mental performance and attentiveness, without stimulating the signs of productive psychopathological disorders: pathological emotional activity and delusions.

After use, Adaptol is absorbed quite well through the gastrointestinal tract - 77-80 percent of the drug. After half an hour, the maximum concentration of the active substance is observed in the blood plasma. This indicator remains at a stable level for 3-4 hours, after which it begins to gradually decrease. The active component of Adaptol is not metabolized and does not accumulate in body tissues.

Most of the drug (55-70 percent) leaves the body with urine, the remaining part - with feces unchanged throughout the day.

Analogs

You can replace the drug with drugs that have the same or similar mechanism of action. The following medications are analogues of adaptol in composition:

• Mebicar;
• Mebix;
• Mebicar-IC;
• Mebikar-Tathimpharm.

The last of the listed drugs is a Russian analogue and is produced in Kazan. The advantage of Russian-made Mebikar is its relatively low cost.

Reviews

Artem M .: “I started having mental problems after several years of hard work with almost no days off. I couldn’t sleep, I was constantly irritated, became aggressive, and couldn’t concentrate. The doctor prescribed me adaptol. I took 3 pills a day. The effect came quickly. At first I noticed that I became calmer, it was almost impossible to anger me. Then my sleep improved and my attention was restored. I’ve been taking this product for two months now.”

Irina P .: “After severe stress, I began to notice a decrease in memory, concentration and overall deterioration in well-being. My mood was constantly changing - I wanted to cry or laugh for no reason. At first, the doctor prescribed me piracetam to improve my memory, but it had no effect on my mood at all. After this, piracetam was replaced with adaptol. The drug helped me, but caused a strong decrease in blood pressure. It took several days to get used to taking it. Now the pressure has recovered, I continue to take the medicine.”

Doctor's review : “Adaptol is the lightest tranquilizer currently known. It does not so much have a sedative effect as it improves the patient’s adaptation to the stressful situation that caused the mental disorder. The basis of many pathological conditions is stress and the lack of adequate ways to deal with it. This leads to dysfunction of many brain structures. Adaptol helps fight stress and normalizes the balance of substances in the central nervous system. First of all, this drug is recommended for people with neurotic and neurosis-like diseases.”

Content

Adaptol | Russian analogues of drugs with prices and reviews

Adaptol is a drug of a special group. It is necessary not to eliminate pain symptoms or inflammatory processes, but in situations that often interfere with living a full life no less than unbearable pain. Anxiety, stress, neuroses - all these are indications for its use.

In most cases, the use of drugs of this type is not the desire of the patient, but the strict prescription of the doctor. This type of medication should not be prescribed to children on their own. Thus, adaptol is contraindicated for use in children under 10 years of age.

The average price for this drug in pharmacies is 624 rubles. Variations of the active ingredients allow you to choose Russian analogues of Adaptol at a price with a less noticeable loss for the budget and with a distinct list of recommendations or side effects.

Russian-made analogues

A large number of registered tablets leaves pharmacy visitors to make their own choice, focusing on a price that is acceptable to everyone.

The list of Russian-made analogues with similar indications for use is large.

Ukrainian substitutes

Most often, when studying the global pharmaceutical market, Ukrainian-made drugs turn out to be the cheapest, but upon closer study it becomes clear that the price range is as great as in other countries.

Cheap analogues of the drug:

1. Mebikar , a drug with the same name as that of Russian manufacturers, but the price starts from 190 rubles. The same list of indications: nervous excitability, irritability, neuropsychic disorders.
2. Tranquilar - its price is higher: 500-600 rubles. The composition contains similar substitutes that affect the restoration of the nervous system, eliminating unreasonable anxieties, fears and excessive irritability.
3. NOOBUT-IC . Made with phenibut. Suitable for children from three years old. Costs about 550 rubles. Used for severe cases of alcohol syndrome.
4. Glyceside . The Ukrainian-made drug is cheaper, costs about 70-100 rubles. Has a slight sedative effect. Gently soothes, brings the general condition back to normal.

Belarusian generics

Belarusian generics are not so numerous, because it is impossible to list all the drugs. The table below contains the names of the most popular ones.

Other foreign analogues

Due to their foreign production, imported medicines seem much better than local ones, but by and large their high price is not always justified. And on the local market there are drugs of equal quality.

Don't forget! The best drug for each specific case should be selected in consultation with a specialist.

List of medicines from abroad:

• Etifoxine . Manufacturer – France. A tranquilizer prescribed by doctors for anxiety, stress, and an unconscious feeling of fear. Or even in a bad mood. A synonym for this drug is Stresam. The average price is 316-505 rudders.
• Neurovitan , produced in Jordan. A vitamin complex aimed at strengthening the nervous system and the body’s correct reactions to stressful situations. Price 450-790 rubles. The medicine contains B vitamins.
• Noofen . Made in Latvia. Prescribed for the treatment of children from the age of three with stuttering or tics. Suitable for adult patients with neuroses. It differs from similar drugs in being easily digestible and tolerable. There are no side effects. Costs about 850 rubles.
• Persen . Made in Poland. The composition includes components of plant origin. They have a mild sedative effect. There are variations of the drug to improve sleep, to establish a general emotional state and to improve the functioning of the cardiovascular system.
• Glycine . The manufacturer is registered in Germany. It is inexpensive, about 140 rubles. Available in powder form for oral administration.

Human health includes several components. Psycho-emotional state is no less important than physical health. To keep your emotions under control, you should not refuse to take medications to relieve stress, fears and nervousness.

Moreover, replacing an expensive, popular drug with a cheap one gives no worse effect. If you are happy, then the people around you will be happy!

Source:

What to choose Adaptol or its analogues: which is better, safer and cheaper?

Adaptol, produced in tablets, is a tranquilizer; its action is aimed at relieving pain symptoms and anxiety, relieving panic attacks, mental stress, unreasonable fears, and pathological irritability.

The drug is based on tetramethyltetraazabicyclooctanedione (in other words, mebicar), a chemical compound that acts similarly to a natural metabolite in the human body.

The active component dulls the intensity of activity of the part of the brain responsible for the emotional background.

Advantages and disadvantages of the drug

Adaptol affects human brain activity quite mildly and does not cause side effects that are common among other analogues, such as dizziness, loss of coordination, weakening of muscle tone, dullness of reaction or euphoria.

The drug is well suited for patients with neuroses, cravings for smoking, and is used during menopause or oxidative stress.

The medicine quickly spreads throughout the body (the initial effect can be observed after 15-20 minutes), the duration of the achieved effect lasts up to 3-4 hours - the patient feels peace and tranquility.

Stress will no longer bother the patient. The drug does not have a toxic effect on the liver and is excreted from the body by the kidneys.

Adaptol is not addictive, patients do not experience withdrawal symptoms. When taking the drug, there are no contraindications for driving vehicles and machinery, or performing work that requires increased attention.

A mild tranquilizing effect, prevents the occurrence of seizures, prevents impairment of motor functions and loss of orientation in space. In general, the effect of taking the drug is the correction and stabilization of mood, clarification of thinking, and increased productivity.

The disadvantages of Adaptol include its price (the average cost in Russia fluctuates around 750 rubles); many of its analogues are cheaper. Taking the medication cannot be combined with alcoholic beverages, so you will have to stay away from entertainment during the treatment.

Analogues of the drug

Like any other drugs, Adaptol has a number of noteworthy analogues, this is the name for medications that, according to their pharmacological indications for use, are similar to the required drug.

Among analogue products, you can always choose a less advertised but effective medicine, with a lower cost and good reviews. The price, as a rule, includes a budget for advertising and organized work to promote the brand in the market. Is it worth paying for it?

So, first of all, it is worth considering the structural analogues of Adaptol, determined by the content of the main active ingredient, it is worth highlighting the following:

• Mebikar (Ukraine);
• Mebikar-Tathimpharm (Russia);
• Mebix (Russia);
• Tranquilar (Ukraine).

There are other substitutes for Adaptol, each of which has its own characteristics, let’s briefly consider the most popular:

1. Trivalumen is often prescribed in complex therapy to patients suffering from insomnia due to fatigue. The drug is also effective in cases of lack of appetite, diagnosed neurocirculatory dystonia with cardiac arrhythmias.
2. Dormiplant is recommended for increased anxiety, restlessness, insomnia, against the background of chronic stress or a state of nervous exhaustion.
3. Sedavit has a wide range of uses. Among the main problems: long-term, psychological, emotional stress, neurasthenia, irritability, impaired memory or concentration. Helps relieve migraines and eliminate headaches.
4. Neuroximet is used for age-related changes (deterioration of memory, mental abilities), cerebral circulatory disorders. Prescribed for the prevention of relapse and complications after a stroke or traumatic brain injury, seasickness. Consultation with your attending physician is required.
5. Pentovit is a good addition in the treatment of diseases of the nervous system (radiculitis, neuralgia, neuritis, nerve inflammation, asthenic condition, weakness, etc.).
6. Cerebrolysin is widely used in the treatment of pathologies associated with malfunctions of the central nervous system, cerebral circulation, psychiatric diseases, problems with absent-mindedness, and memory loss.
7. Diphenin has a targeted effect for the relief of grand mal seizures, treatment of status epilepticus with tonic-clonic seizures, and prevention of seizures in neurosurgery.
8. Omaron is applicable for disorders of various etiologies, which are related to cerebral circulation disorders due to traumatic brain injury, ischemic or hemorrhagic stroke. The list of indications for use also includes atherosclerosis, encephalopathy, memory loss, attention impairment, mood swings, asthenic syndrome, migraine attacks, etc.
9. Sedinal is recommended to be added to the daily diet as a general strengthening drug; it has a gentle and soothing effect. It has a beneficial effect when enhancing the psycho-emotional state.
10. Extal-3 (calming) stabilizes the general condition in case of excessive irritability, stress or depression. Corrects sleep disorders, psychosomatic disorders and withdrawal symptoms.
11. Nevrin is often prescribed after strokes, for neuroses and depression, and neurocirculatory disorders. Indications may include head trauma, acute cerebrovascular accidents.

Source: https://tovaridljazdorovja.ru/otzyvy/adaptol-rossijskie-analogi-lekarstv-s-tsenami-i-otzyvami.html